Oxygen therapy is the important method of critical care especially to pediatric patients of post-open heart surgery. The purpose of this study is to investigate the effect of oxygen therapy with modified T-piece in pediatric patients. We supply
oxygen
via modified T-piece after ventilatory weaning as following rates in turn: group 1; 0.05L/min/kg, group 2; 0.1L/min/kg, group 3; 0.3L/min/kg, group 4; 0.5L/min/kg. Arterial blood gas analysis was done and heart rate, systolic and diastolic blood
pressure, body temperature and oxygen saturation were recorded. W defined absolute oxygen flow as oxygen flow/weight×weight. The relationshiop between oxygen flow/weight or absolute oxygen flow and PaO2, SaO2 was statistically significant. We
got
the
regression equation as following; PaO2=119.7×oxygen flow/weight+132.7 (R²=0.13), SaO2=3.2×oxygen flow/weight+97.9 (R²=0.11), PaO2=6.7×absolute oxygen flow+141.6 (R²=0.11), SaO2=0.16×absolute oxygen flow+98.2 (R²=0.1). There were
significant
factors, by which PaO2 was influenced, such as oxygen flow/weight (Pearson correlation coefficient, r=0.34), absolute oxygen flow (r=0.37), SaO2 (r=0.57), heart rate (r=-0.35), body temperature (r=0.21). @ES As the result of mutiple regression
analysis
of the these factors, we got the regression equation as following; @EN PaO2=-1254.8+67.1×oxygen flow/weight+14.5×SaO2-1.6×PaCO2-0.5×heart×rate+2.7×body temperature (R²=0.44). PaO2--1240+5.4×absolute oxygen flow+14.0×SaO2-1.4
PaCO2-0.6×heart
rate+4.0 body temperature-2.1×weight (R²=0.46).
It were group 1; 0.66, group 2; 0.69, group 3; 0.71, group 4; 0.75 that were calculated FIO2 using AaDO2 in case of FIO2=1.0 and increased significantly. However, because R² that we got in the regression equation is too small, even though there
is
statistical significance, we think that clinical application of the result of our study is difficult.
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